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Patient Resources

Patient Resources

SYNTHROID is contraindicated in patients with uncorrected adrenal insufficiency see WARNINGS AND PRECAUTIONS. Long-term carcinogenicity studies in animals to evaluate the carcinogenic potential of levothyroxine have not been performed. Studies to evaluate mutagenic potential and animal fertility have not been performed.

4 Monitoring TSH and/or Thyroxine (T Levels

Levoxyl treats hypothyroidism (low thyroid hormone) and treats or prevents goiter. SYNTHROID is not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients, as there are no clinical benefits and overtreatment with SYNTHROID may induce hyperthyroidism. By visiting Synthroid.com, patients can access additional support and resources to understand and manage their hypothyroidism. The Before Breakfast Club is a program designed to help support your patients on SYNTHROID therapy. After joining, patients will receive exclusive benefits including savings, tips, and tools to help your patients make the most of their SYNTHROID treatment.

Patient resources

Protein-bound thyroid hormones exist in reverse equilibrium with small amounts of free hormone. Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see Drug Interactions (7). Thyroid hormones do not readily cross the placental barrier see Use in Specific Populations (8.1). Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see DRUG INTERACTIONS. Thyroid hormones do not readily cross the placental barrier see Use In Specific Populations. Myxedema coma is a life-threatening emergency characterized by poor circulation and hypometabolism and may result in unpredictable absorption of levothyroxine sodium from the gastrointestinal tract.

RxList does not provide medical advice, diagnosis or treatment. Administer SYNTHROID as a single daily dose, on an empty stomach, one-half to one hour before breakfast. Pregnant and lactating females need to discuss the dose and use of this medication with their caregivers. This document does not contain all possible side effects and others may occur.

  • Dr. Frieze suggests educating patients on the importance of consistent therapy & precise dosing with Synthroid.
  • For adult patients with primary hypothyroidism, titrate until the patient is clinically euthyroid and the serum TSH returns to normal see Recommended Dosage And Titration.
  • The estimated background risk of major birth defects and miscarriage for the indicated population is unknown.
  • Your child’s dose needs may change if the child gains or loses weight.
  • Titrate the dose of SYNTHROID carefully and monitor response to titration to avoid these effects see DOSAGE AND ADMINISTRATION.

Consider the potential for food or drug interactions and adjust the administration or dosage of SYNTHROID as needed see Dosage and Administration (2.1), Drug Interactions (7.1), and Clinical Pharmacology (12.3). The signs and symptoms of overdosage are those of hyperthyroidism see WARNINGS AND PRECAUTIONS and Adverse Reactions. Seizures occurred in a 3-yearold child ingesting 3.6 mg of levothyroxine. Titrate the dose of SYNTHROID carefully and monitor response to titration to avoid these effects see DOSAGE AND ADMINISTRATION. Consider the potential for food or drug interactions and adjust the administration or dosage of SYNTHROID as needed see DOSAGE AND ADMINISTRATION, DRUG INTERACTIONS and CLINICAL PHARMACOLOGY.

NP Thyroid

Tell your doctor if you have an untreated or uncontrolled adrenal gland disorder, a thyroid disorder called thyrotoxicosis, or if you have any recent or current symptoms of a heart attack. Biochemical assessment incorporated measurement of serum TSH, T3, and T4. TSH lower limit of quantification was 0.2 mIU/L and upper limit of normal was 5.6 mIU/L, as indicated by the shaded area. SYNTHROID is not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis. With the Synthroid Delivers Program, everyone with a Synthroid prescription pays the same price, every time, with no hidden out-of-pocket costs or price fluctuations.

  • In order for Synthroid to be effective, it should always be taken the same way every day.
  • Our Synthroid Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
  • Triiodothyronine (T3) and L-thyroxine (T4) diffuse into the cell nucleus and bind to thyroid receptor proteins attached to DNA.
  • Notify your doctor if you experience serious side effects of Synthroid including rapid heartbeat, fluttering in your chest, or chest pain.
  • In addition, many drugs and foods affect T4 absorption see DRUG INTERACTIONS.
  • In addition, many drugs and foods affect T4 absorption see Drug Interactions (7).

Check with your physician for additional information about side effects. Notify your doctor if you experience serious side effects of Synthroid including rapid heartbeat, fluttering in your chest, or chest pain. Get medical help right away, if you have any of the symptoms listed above. Always consult your healthcare provider to ensure the information displayed on this page synthroid lpr applies to your personal circumstances. Enter medications to view a detailed interaction report using our Drug Interaction Checker. Do not share this medicine with another person, even if they have the same symptoms you have.

  • Therefore, initiate SYNTHROID therapy immediately upon diagnosis.
  • Thyroid hormones do not readily cross the placental barrier see Use In Specific Populations.
  • TSH is produced by a small gland in the brain called the pituitary and can be measured by a common blood test.
  • Doctors often may have to slowly increase the dose; patients should not increase or decrease this medication themselves.

A TSH test is used to check the level of thyroid-stimulating hormone in the blood. Your TSH level can indicate if your thyroid gland is working properly. With hypothyroidism, the thyroid is unable to produce enough thyroid hormone. Thyroid hormone levels in the body provide signals to the hypothalamus and pituitary, so they know whether to release more or less TRH and TSH.

Adverse Reactions/Side Effects

Synthroid is also used in patients who need surgery and radioiodine therapy to manage a type of thyroid cancer called well-differentiated thyroid cancer. The hypothalamus and pituitary react to these low levels of thyroid hormone by producing more TRH and TSH. Biotin supplementation is known to interfere with thyroid hormone immunoassays that are based on a biotin and streptavidin interaction, which may result in erroneous thyroid hormone test results. Stop biotin and biotin-containing supplements for at least 2 days prior to thyroid testing. The SYNTHROID dosage is based on the target level of TSH suppression for the stage and clinical status of thyroid cancer. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown.

My consent is required to process sensitive personal data under certain privacy laws, and I have the right to withdraw my consent by visiting “Your Privacy Choices” on AbbVie’s website. SYNTHROID is contraindicated in patients with uncorrected adrenal insufficiency see Warnings and Precautions (5.4). Administer SYNTHROID at least 4 hours before or after drugs known to interfere with SYNTHROID absorption see Drug Interactions (7.1). A portion of the conjugated hormone reaches the colon unchanged and is eliminated in the feces.

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